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KMID : 0861019990140010149
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Korea Journal of Herbology
1999 Volume.14 No. 1 p.149 ~ p.152
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Effect of Deer Antler on the Blood Pressure and Heart Rate of SHR and S. D. Rats
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安德均/Ahn, Duk Kyun
金護哲/李福男/Kim, Ho Cheol/Lee, Bok Nam
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Abstract
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Cornu Cervi Elapi, which is dried unossificated juvenile antler of Cervus nippon Temminck or C. elaphus E maral. was recorded first in and has been used as one of the most important reinforcing drugs. Generally reinforcing the kidney-yang drugs such as Oriental aconite, Cinnamomi cortex spissus, also strongly affect cardiovascular system. So it has some meaning for clinical treatment and prevention to study the effect of deer antler on cardiovascular system.
We used C. elaphus L. from New Zealand. The change of blood pressure in SHR after oral administration of 70% measured in carotid artery of S.D rats after intravenous administration. The effect on normal blood pressure was measured in carotid artery of S.D rats after intravenous administration. The percent changes of blood pressure was calculated and compared to the control group which was administered with normal saline.
In SHR rats, blood pressure has decreased with the rate of 2.9±2.6 %, 2.9±1.9 %, 6.0±2.6 %, and 1.3±2.6 % compared to the control group, In normotensive rats, blood pressure showed tendency to increase rather than decrease after intravenous administration of the drug, but there´s no statistical significance.
According to this result, it is concluded that C. elaphus L. from New Zealand hardly affects on blood pressure and heart rates.
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